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What Esomeprazole is and what it is used for:

•Esomeprazole belongs to a group of medicines called ‘proton pump inhibitors’. They work by reducing the amount of acid that your stomach produces.
This medicine is used in adults for the short term treatment of reflux symptoms (for example, heartburn and acid regurgitation).
•Reflux is the backflow of acid from the stomach into the gullet (“foodpipe”) which may become inflamed and painful. This may cause you symptoms such as a painful sensation in the chest rising up to your throat (heartburn) and a sour taste in the mouth (acid regurgitation).
•Esomeprazole is not meant to bring immediate relief. 
•You may need to take the capsules for 2-3 days in a row before you feel better. You must talk to a doctor if you do not feel better or if you feel worse after 14 days.


What you need to know before you use Esomeprazole:

Do not use Esomeprazole:
If   you   are   allergic to Esomeprazole   or any   of   the   other   ingredients in   this medicine
If you are allergic to medicines containing other proton pump inhibitors (e.g. pantoprazole, lansoprazole, rabeprazole or omeprazole).
If you are taking a medicine containing nelfinavir (used to treat HIV infection).


Warnings and precautions:
You   should   let   your   doctor   know:
You have had a stomach ulcer or stomach surgery in the past.
You have been taking treatment continuously for reflux or heartburn for 4 or more weeks.
You have jaundice (yellowing of skin or eyes) or severe liver problems.
You have severe kidney problems.
You are aged over 55 years and have new or recently changed reflux symptoms or need to take a non-prescription indigestion or heartburn remedy treatment every day.
You have ever had a skin reaction after treatment with a medicine similar to Esomeprazole that reduces stomach acid.
You are due to have an endoscopy or a urea breath test.
You are due to have a specific blood test (Chromogranin A). 

Other medicines and Esomeprazole:
•Do not take this medicine if you are also taking a medicine containing nelfinavir (used to treat HIV infection). 
•You should specifically tell your doctor or pharmacist if you are taking clopidogrel (used to prevent blood clots). 
•Do not take this medicine with other medicines that limit the amount of acid produced in your stomach such as proton pump inhibitors (e.g. pantoprazole, lansoprazole, rabeprazole or omeprazole) or an H2 antagonist (e.g. ranitidine or famotidine)

Inform your doctor about the medicines you are taking, especially mention to you doctor if you are taking:
Ketoconazole and itraconazole (used to treat infections caused by a fungus).
Voriconazole (used to treat infections caused by a fungus) and clarithromycin (used to treat infections). Your doctor may adjust your dose of Esomeprazole if you also have severe liver problems and are treated for a long period of time.
Erlotinib (used to treat cancer).
Methotrexate (used to treat cancer and rheumatic disorders).
Digoxin (used for heart problems).
Atazanavir, saquinavir (used to treat HIV infection).
Citalopram, imipramine or clomipramine (used to treat depression).
Diazepam (used to treat anxiety, relax muscles or in epilepsy).
Phenytoin (used to treat epilepsy).
Medicines that are used to thin your blood, such as warfarin. Your doctor may need to monitor you when you start or stop taking Esomeprazole.
Cilostazol (used to treat intermittent claudication – a condition where poor blood supply to the leg muscles causes pain and difficulty in walking).
Cisapride (used for indigestion and heartburn).
Rifampicin (used to treat tuberculosis).
Tacrolimus (in cases of organ transplantation).
St. John’s wort (Hypericum perforatum) (used to treat depression). risk of a lowered threshold for seizures.

Children and adolescents: 
Esomeprazole should normally not be used for children and adolescents under 18 years.

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Nexium 40 mg Tablet 14pcs

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